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MetabolismApproved · EU/US

Semaglutid

Semaglutide · GLP-1 receptor agonist

Semaglutide is a GLP-1 receptor agonist used in approved medicines. Indication, formulation and dosing depend on the specific product.

Approvals

EU · ApprovedUS · Approved

Peptipedia explains research and prescribing information. It does not replace medical advice and is not an invitation to use a substance.

Research areas

Weight managementMetabolismMASH

Evidence matrix

Molecular identity
Confirmed

Semaglutide is a defined GLP-1 analogue. This profile distinguishes approved Wegovy formulations by region; salts and research products are not equivalent.

Human research
Strong
Replication
Multiple independent groups
Clinical endpoints
Hard patient-relevant outcomes
Safety
Characterized by prescribing information or extensive studies
Approval
EU · ApprovedUS · Approved

The dimensions are presented separately and are not combined into an overall score.

Current approval context

EU and US product information differ; the US label includes a MASH indication.

Research gaps

  • ·Results depend on the studied population, region and specific product.